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Enzymatic Characterization of a Mutant of Escherichia coli with an Altered DNA Ligase

A temperature-sensitive, radiation-sensitive mutant of Escherichia coli has been assayed for DNA ligase activity in vitro. The strain contains a markedly reduced amount of DNA-joining activity, which is thermolabile. The formation of the ligase-adenylate intermediate is also temperature-sensitive in...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Modrich, Paul, Lehman, I. R.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1971
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389100/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4995816/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.5.1002
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