Role of caspase-8 in thymus function

The thymus is the primary organ responsible for de novo generation of immunocompetent T cells that have a diverse repertoire of antigen recognition. During the developmental process, 98% of thymocytes die by apoptosis. Thus apoptosis is a dominant process in the thymus and occurs through either deat...

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Bibliografske podrobnosti
Main Authors: Pozzesi, N, Fierabracci, A, Liberati, A M, Martelli, M P, Ayroldi, E, Riccardi, C, Delfino, D V
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890959/
https://ncbi.nlm.nih.gov/pubmed/24270406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.166
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