Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility

Expression of receptor for hyaluronan-mediated motility (RHAMM), a breast cancer susceptibility gene, is tightly controlled in normal tissues but elevated in many tumors, contributing to tumorigenesis and metastases. However, how the expression of RHAMM is regulated remains elusive. Statins, inhibit...

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Detalles Bibliográficos
Autores principales: Wang, Zhongyuan, Wu, Yanping, Wang, Haifeng, Zhang, Yangqing, Mei, Lin, Fang, Xuexun, Zhang, Xudong, Zhang, Fang, Chen, Hongbo, Liu, Ying, Jiang, Yuyang, Sun, Shengnan, Zheng, Yi, Li, Na, Huang, Laiqiang
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2014
Materias:
PNAS Plus
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890879/
https://ncbi.nlm.nih.gov/pubmed/24367099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319190110
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