Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility

Expression of receptor for hyaluronan-mediated motility (RHAMM), a breast cancer susceptibility gene, is tightly controlled in normal tissues but elevated in many tumors, contributing to tumorigenesis and metastases. However, how the expression of RHAMM is regulated remains elusive. Statins, inhibit...

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Detalhes bibliográficos
Main Authors: Wang, Zhongyuan, Wu, Yanping, Wang, Haifeng, Zhang, Yangqing, Mei, Lin, Fang, Xuexun, Zhang, Xudong, Zhang, Fang, Chen, Hongbo, Liu, Ying, Jiang, Yuyang, Sun, Shengnan, Zheng, Yi, Li, Na, Huang, Laiqiang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890879/
https://ncbi.nlm.nih.gov/pubmed/24367099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319190110
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