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Tonic GABA(A) conductance bidirectionally controls interneuron firing pattern and synchronization in the CA3 hippocampal network

The spiking output of interneurons is key for rhythm generation in the brain. However, what controls interneuronal firing remains incompletely understood. Here we combine dynamic clamp experiments with neural network simulations to understand how tonic GABA(A) conductance regulates the firing patter...

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Bibliografiska uppgifter
Huvudupphovsmän: Pavlov, Ivan, Savtchenko, Leonid P., Song, Inseon, Koo, Jaeyeon, Pimashkin, Alexey, Rusakov, Dmitri A., Semyanov, Alexey
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2014
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890854/
https://ncbi.nlm.nih.gov/pubmed/24344272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308388110
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