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Tonic GABA(A) conductance bidirectionally controls interneuron firing pattern and synchronization in the CA3 hippocampal network

The spiking output of interneurons is key for rhythm generation in the brain. However, what controls interneuronal firing remains incompletely understood. Here we combine dynamic clamp experiments with neural network simulations to understand how tonic GABA(A) conductance regulates the firing patter...

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Hlavní autoři: Pavlov, Ivan, Savtchenko, Leonid P., Song, Inseon, Koo, Jaeyeon, Pimashkin, Alexey, Rusakov, Dmitri A., Semyanov, Alexey
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890854/
https://ncbi.nlm.nih.gov/pubmed/24344272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308388110
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