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The antigen 43 structure reveals a molecular Velcro-like mechanism of autotransporter-mediated bacterial clumping

Aggregation and biofilm formation are critical mechanisms for bacterial resistance to host immune factors and antibiotics. Autotransporter (AT) proteins, which represent the largest group of outer-membrane and secreted proteins in Gram-negative bacteria, contribute significantly to these phenotypes....

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Detalhes bibliográficos
Main Authors: Heras, Begoña, Totsika, Makrina, Peters, Kate M., Paxman, Jason J., Gee, Christine L., Jarrott, Russell J., Perugini, Matthew A., Whitten, Andrew E., Schembri, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890832/
https://ncbi.nlm.nih.gov/pubmed/24335802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311592111
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