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Covalent Attachment of Diethylstilbestrol to Glutamate Dehydrogenase: Implications for Allosteric Regulation

An affinity labeling reagent for the estrogenic-binding site of bovine liver L-glutamate dehydrogenase (EC 1.4.1.3) was prepared by conversion of diethylstilbestrol to its alkylating analogue, bromoacetyldiethylstilbestrol. Under standard assay conditions, the analogue acted as a reversible alloster...

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Autors principals: Kallos, John, Shaw, K. P.
Format: Artigo
Idioma:Inglês
Publicat: 1971
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC389080/
https://ncbi.nlm.nih.gov/pubmed/4325003
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