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Covalent Attachment of Diethylstilbestrol to Glutamate Dehydrogenase: Implications for Allosteric Regulation

An affinity labeling reagent for the estrogenic-binding site of bovine liver L-glutamate dehydrogenase (EC 1.4.1.3) was prepared by conversion of diethylstilbestrol to its alkylating analogue, bromoacetyldiethylstilbestrol. Under standard assay conditions, the analogue acted as a reversible alloster...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Kallos, John, Shaw, K. P.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1971
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389080/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4325003/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.5.916
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