Covalent Attachment of Diethylstilbestrol to Glutamate Dehydrogenase: Implications for Allosteric Regulation
An affinity labeling reagent for the estrogenic-binding site of bovine liver L-glutamate dehydrogenase (EC 1.4.1.3) was prepared by conversion of diethylstilbestrol to its alkylating analogue, bromoacetyldiethylstilbestrol. Under standard assay conditions, the analogue acted as a reversible alloster...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1971
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389080/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4325003/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.5.916 |
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