Cytosine 5-Hydroxymethylation of the LZTS1 Gene Is Reduced in Breast Cancer

Change of DNA cytosine methylation (5mC) is an early event in the development of cancer, and the recent discovery of a 5-hydroxymethylated form (5hmC) of cytosine suggests a regulatory epigenetic role that might be different from 5-methylcytosine. Here, we aimed at elucidating the role of 5hmC in br...

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Detalhes bibliográficos
Main Authors: Wielscher, Matthias, Liou, Willy, Pulverer, Walter, Singer, Christian F, Rappaport-Fuerhauser, Christine, Kandioler, Daniela, Egger, Gerda, Weinhäusel, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890706/
https://ncbi.nlm.nih.gov/pubmed/24466374
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