Discovery of MLL1 binding units, their localization to CpG Islands, and their potential function in mitotic chromatin

BACKGROUND: Mixed Lineage Leukemia 1 (MLL1) is a mammalian ortholog of the Drosophila Trithorax. In Drosophila, Trithorax complexes transmit the memory of active genes to daughter cells through interactions with Trithorax Response Elements (TREs). However, despite their functional importance, nothin...

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Main Authors: Bina, Minou, Wyss, Phillip, Novorolsky, Elise, Zulkelfi, Noorfatin, Xue, Jing, Price, Randi, Fay, Matthew, Gutmann, Zach, Fogler, Brian, Wang, Daidong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890651/
https://ncbi.nlm.nih.gov/pubmed/24373511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-927
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