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Purification and DNA Synthesis in Cell-Free Extracts: Properties of DNA Polymerase II

The major DNA-synthesizing enzyme present in Pol A(1)(-)Escherichia coli (DNA polymerase II) has been purified to homogeneity as judged by polyacrylamide gel electrophoresis. The enzyme requires all four deoxynucleoside triphosphates, Mg(++), NH(4)(+), and native DNA for maximal activity. The enzyme...

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Bibliografiske detaljer
Main Authors: Kornberg, Thomas, Gefter, Malcolm L.
Format: Artigo
Sprog:Inglês
Udgivet: 1971
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC389037/
https://ncbi.nlm.nih.gov/pubmed/4927672
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