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ARP2/3-mediated junction-associated lamellipodia control VE-cadherin–based cell junction dynamics and maintain monolayer integrity

Maintenance and remodeling of endothelial cell junctions critically depend on the VE-cadherin/catenin complex and its interaction with the actin filament cytoskeleton. Here we demonstrate that local lack of vascular endothelial (VE)-cadherin at established cell junctions causes actin-driven and acti...

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Bibliographische Detailangaben
Hauptverfasser: Taha, Abdallah Abu, Taha, Muna, Seebach, Jochen, Schnittler, Hans-J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890345/
https://ncbi.nlm.nih.gov/pubmed/24227887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-07-0404
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