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Chloride Channel-Targeted Therapy for Secretory Diarrheas

Secretory diarrheas caused by bacterial and viral enterotoxins remain a significant cause of morbidity and mortality. Enterocyte Cl(−) channels represent an attractive class of targets for diarrhea therapy, as they are the final, rate-limiting step in enterotoxin-induced fluid secretion in the intes...

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Détails bibliographiques
Auteurs principaux: Thiagarajah, Jay R., Verkman, A.S.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890324/
https://ncbi.nlm.nih.gov/pubmed/23992767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2013.08.005
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