Diversity of Prdm9 Zinc Finger Array in Wild Mice Unravels New Facets of the Evolutionary Turnover of this Coding Minisatellite

In humans and mice, meiotic recombination events cluster into narrow hotspots whose genomic positions are defined by the PRDM9 protein via its DNA binding domain constituted of an array of zinc fingers (ZnFs). High polymorphism and rapid divergence of the Prdm9 gene ZnF domain appear to involve posi...

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Autors principals: Buard, Jérôme, Rivals, Eric, Dunoyer de Segonzac, Denis, Garres, Charlotte, Caminade, Pierre, de Massy, Bernard, Boursot, Pierre
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890296/
https://ncbi.nlm.nih.gov/pubmed/24454780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085021
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