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Molecular alterations in proteasomes of rat liver during aging result in altered proteolytic activities

Aging induces alterations of tissue protein homoeostasis. To investigate one of the major systems catalysing intracellular protein degradation we have purified 20S proteasomes from rat liver of young (2 months) and aged (23 months) animals and separated them into three subpopulations containing diff...

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Main Authors: Gohlke, Sabrina, Mishto, Michele, Textoris-Taube, Kathrin, Keller, Christin, Giannini, Carolin, Vasuri, Francesco, Capizzi, Elisa, D’Errico-Grigioni, Antonia, Kloetzel, Peter-Michael, Dahlmann, Burkhardt
格式: Artigo
語言:Inglês
出版: Springer Netherlands 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889881/
https://ncbi.nlm.nih.gov/pubmed/23690132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-013-9543-x
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