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Molecular alterations in proteasomes of rat liver during aging result in altered proteolytic activities

Aging induces alterations of tissue protein homoeostasis. To investigate one of the major systems catalysing intracellular protein degradation we have purified 20S proteasomes from rat liver of young (2 months) and aged (23 months) animals and separated them into three subpopulations containing diff...

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Bibliografische gegevens
Hoofdauteurs: Gohlke, Sabrina, Mishto, Michele, Textoris-Taube, Kathrin, Keller, Christin, Giannini, Carolin, Vasuri, Francesco, Capizzi, Elisa, D’Errico-Grigioni, Antonia, Kloetzel, Peter-Michael, Dahlmann, Burkhardt
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Netherlands 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889881/
https://ncbi.nlm.nih.gov/pubmed/23690132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-013-9543-x
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