Negative impact of βarrestin1 on post-myocardial infarction heart failure via cardiac and adrenal-dependent neurohormonal mechanisms

βarrestin (βarr)-1 and -2 (βarrs) are universal G protein-coupled receptor adapter proteins that negatively regulate cardiac β–adrenergic receptor (βAR) function via βAR desensitization & downregulation. In addition, they mediate G protein-independent βAR signaling, which might be beneficial, e....

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Autores principales: Bathgate-Siryk, Ashley, Dabul, Samalia, Pandya, Krunal, Walklett, Karlee, Rengo, Giuseppe, Cannavo, Alessandro, De Lucia, Claudio, Liccardo, Daniela, Gao, Erhe, Leosco, Dario, Koch, Walter J., Lymperopoulos, Anastasios
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889868/
https://ncbi.nlm.nih.gov/pubmed/24218435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.113.02043
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