Nanosized zinc oxide particles do not promote DHPN-induced lung carcinogenesis but cause reversible epithelial hyperplasia of terminal bronchioles

Zinc oxide (ZnO) is known to induce lung toxicity, including terminal bronchiolar epithelial hyperplasia, which gives rise to concerns that nanosized ZnO (nZnO) might lead to lung carcinogenesis. We studied the tumor promoting activity of nZnO by an initiation–promotion protocol using human c-Ha-ras...

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Bibliografische gegevens
Hoofdauteurs: Xu, Jiegou, Futakuchi, Mitsuru, Alexander, David B., Fukamachi, Katsumi, Numano, Takamasa, Suzui, Masumi, Shimizu, Hideo, Omori, Toyonori, Kanno, Jun, Hirose, Akihiko, Tsuda, Hiroyuki
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Berlin Heidelberg 2013
Onderwerpen:
Inorganic Compounds
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889829/
https://ncbi.nlm.nih.gov/pubmed/23832296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-013-1086-5
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