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Anthrax toxin induces macrophage death by p38 MAPK inhibition but leads to inflammasome activation via ATP leakage

Detection of microbial constituents by membrane associated and cytoplasmic pattern recognition receptors is the essence of innate immunity, leading to activation of protective host responses. However, it is still unclear how immune cells specifically respond to pathogenic bacteria. Using virulent an...

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Detaylı Bibliyografya
Asıl Yazarlar: Ali, Syed Raza, Timmer, Anjuli M., Bilgrami, Sameera, Park, Eek Joong, Eckmann, Lars, Nizet, Victor, Karin, Michael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889666/
https://ncbi.nlm.nih.gov/pubmed/21683629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.04.015
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