Proper Development of the Outer Longitudinal Smooth Muscle of the Mouse Pylorus Requires Nkx2-5 and Gata3

BACKGROUND & AIMS: Infantile hypertrophic pyloric stenosis (IHPS) is a common birth anomaly characterized by obstruction of the pyloric lumen. A genome-wide association study implicated NKX2-5, which encodes a transcription factor that is expressed in embryonic heart and pylorus, in the pathogen...

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Main Authors: Udager, Aaron M., Prakash, Ajay, Saenz, David A., Schinke, Martina, Moriguchi, Takashi, Jay, Patrick Y., Lim, Kim-Chew, Engel, James Douglas, Gumucio, Deborah L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889663/
https://ncbi.nlm.nih.gov/pubmed/24120474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.10.008
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