Biochemical Activities of Streptococcus pneumoniae Serotype 2 Capsular Glycosyltransferases and Significance of Suppressor Mutations Affecting the Initiating Glycosyltransferase Cps2E

The capsular polysaccharide (CPS) is essential for Streptococcus pneumoniae virulence. Its synthesis requires multiple enzymes, and defects that block completion of the pathway can be lethal in the absence of secondary suppressor mutations. In this study, we examined the functions of three capsular...

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Main Authors: James, David B. A., Gupta, Kanupriya, Hauser, Jocelyn R., Yother, Janet
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889599/
https://ncbi.nlm.nih.gov/pubmed/24097952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00715-13
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