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Co-administration of 5-HT6 receptor antagonists with clozapine, risperidone, and a 5-HT2A receptor antagonist: effects on prepulse inhibition in rats

RATIONALE: Some novel antipsychotics manifest antagonistic activity at serotonin-6 receptors; however, little is known about the role of 5-HT6 receptors in ameliorating sensory gating deficits. OBJECTIVE: We evaluated the effects of the combined administration of the 5-HT6 receptor antagonist SB 271...

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Bibliographic Details
Main Authors: Fijał, Katarzyna, Popik, Piotr, Nikiforuk, Agnieszka
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889519/
https://ncbi.nlm.nih.gov/pubmed/23954911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-013-3234-2
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