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P2Y(2) receptor agonist with enhanced stability protects the heart from ischemic damage in vitro and in vivo

Extracellular nucleotides acting via P2 receptors play important roles in cardiovascular physiology/pathophysiology. Pyrimidine nucleotides activate four G protein-coupled P2Y receptors (P2YRs): P2Y(2) and P2Y(4) (UTP-activated), P2Y(6), and P2Y(14). Previously, we showed that uridine 5′-triphosphat...

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Bibliografiske detaljer
Main Authors: Hochhauser, Edith, Cohen, Ronit, Waldman, Maayan, Maksin, Anna, Isak, Ahuva, Aravot, Dan, Jayasekara, P. Suresh, Müller, Christa E., Jacobson, Kenneth A., Shainberg, Asher
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889391/
https://ncbi.nlm.nih.gov/pubmed/23828651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-013-9374-3
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