The Role of Heme Oxygenase 1 in the Protective Effect of Caloric Restriction against Diabetic Cardiomyopathy

Type 2 diabetes mellitus (DM2) leads to cardiomyopathy characterized by cardiomyocyte hypertrophy, followed by mitochondrial dysfunction and interstitial fibrosis, all of which are exacerbated by angiotensin II (AT). SIRT1 and its transcriptional coactivator target PGC-1α (peroxisome proliferator-ac...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Waldman, Maayan, Nudelman, Vadim, Shainberg, Asher, Zemel, Romy, Kornwoski, Ran, Aravot, Dan, Peterson, Stephen J., Arad, Michael, Hochhauser, Edith
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6566501/
https://ncbi.nlm.nih.gov/pubmed/31100876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20102427
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