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The Role of Heme Oxygenase 1 in the Protective Effect of Caloric Restriction against Diabetic Cardiomyopathy

Type 2 diabetes mellitus (DM2) leads to cardiomyopathy characterized by cardiomyocyte hypertrophy, followed by mitochondrial dysfunction and interstitial fibrosis, all of which are exacerbated by angiotensin II (AT). SIRT1 and its transcriptional coactivator target PGC-1α (peroxisome proliferator-ac...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Waldman, Maayan, Nudelman, Vadim, Shainberg, Asher, Zemel, Romy, Kornwoski, Ran, Aravot, Dan, Peterson, Stephen J., Arad, Michael, Hochhauser, Edith
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6566501/
https://ncbi.nlm.nih.gov/pubmed/31100876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20102427
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