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Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease
Transforming growth factor-β1 (TGF-β1) is a multifunctional growth factor that has profound regulatory effects on many developmental and physiological processes. Disruption of the TGF-β1 gene by homologous recombination in murine embryonic stem cells enables mice to be generated that carry the disru...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3889166/ https://ncbi.nlm.nih.gov/pubmed/1436033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/359693a0 |
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