Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease

Transforming growth factor-β1 (TGF-β1) is a multifunctional growth factor that has profound regulatory effects on many developmental and physiological processes. Disruption of the TGF-β1 gene by homologous recombination in murine embryonic stem cells enables mice to be generated that carry the disru...

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Bibliografiske detaljer
Main Authors: Shull, Marcia M., Ormsby, Ilona, Kier, Ann B., Pawlowskr, Sharon, Diebold, Ronald J., Yin, Moying, Allen, Ruth, Sidman, Charles, Proetzel, Gabriele, Calvint, Dawn, Annunziata, Nikki, Doetschman, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889166/
https://ncbi.nlm.nih.gov/pubmed/1436033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/359693a0
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