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DREADDs in Drosophila: A Pharmacogenetic Approach for Controlling Behavior, Neuronal Signaling, and Physiology in the Fly

We have translated a powerful genetic tool, designer receptors exclusively activated by designer drugs (DREADDs), from mammalian systems to Drosophila melanogaster to selectively, rapidly, reversibly, and dose-dependently control behaviors and physiological processes in the fly. DREADDs are muscarin...

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Détails bibliographiques
Auteurs principaux: Becnel, Jaime, Johnson, Oralee, Majeed, Zana R., Tran, Vi, Yu, Bangning, Roth, Bryan L., Cooper, Robin L., Kerut, Edmund K., Nichols, Charles D.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889141/
https://ncbi.nlm.nih.gov/pubmed/24012754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.08.003
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