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Active DNA demethylation is required for complete imprint erasure in primordial germ cells
In mammalian primordial germ cells (PGCs), DNA demethylation is indispensible for parental imprint erasure, which is a reprogramming process essential for normal developmental potential. Thus, it is important to elucidate how DNA demethylation occurs in each imprinted region in PGCs and to determine...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3888974/ https://ncbi.nlm.nih.gov/pubmed/24413819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03658 |
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