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Imprinting regulation of the murine Meg1/Grb10 and human GRB10 genes; roles of brain-specific promoters and mouse-specific CTCF-binding sites

The imprinted mouse gene Meg1/Grb10 is expres sed from maternal alleles in almost all tissues and organs, except in the brain, where it is expressed biallelically, and the paternal allele is expressed preferentially in adulthood. In contrast, the human GRB10 gene shows equal biallelic expression in...

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Bibliografiske detaljer
Main Authors: Hikichi, Takafusa, Kohda, Takashi, Kaneko-Ishino, Tomoko, Ishino, Fumitoshi
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC149825/
https://ncbi.nlm.nih.gov/pubmed/12595547
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