Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.

About 300 carcinogens and non-carcinogens of a wide variety of chemical types have been tested for mutagenicity in the simple Salmonella/microsome test. The test uses bacteria as sensitive indicators for DNA damage, and mammalian liver extracts for metabolic conversion of carcinogens to their active...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	McCann, J, Choi, E, Yamasaki, E, Ames, B N
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1975
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388891/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1061098/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.72.12.5135
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