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Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.

About 300 carcinogens and non-carcinogens of a wide variety of chemical types have been tested for mutagenicity in the simple Salmonella/microsome test. The test uses bacteria as sensitive indicators for DNA damage, and mammalian liver extracts for metabolic conversion of carcinogens to their active...

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Bibliographic Details
Main Authors: McCann, J, Choi, E, Yamasaki, E, Ames, B N
Format: Artigo
Language:Inglês
Published: 1975
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC388891/
https://ncbi.nlm.nih.gov/pubmed/1061098
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