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Detecting Chemically Modified DNA Bases Using Surface Enhanced Raman Spectroscopy

Post-translational modifications of DNA- changes in the chemical structure of individual bases that occur without changes in the DNA sequence- are known to alter gene expression. They are believed to result in frequently deleterious phenotypic changes, such as cancer. Methylation of adenine, methyla...

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Detalhes bibliográficos
Main Authors: Barhoumi, Aoune, Halas, Naomi J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3888867/
https://ncbi.nlm.nih.gov/pubmed/24427449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jz201423b
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