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Detecting Chemically Modified DNA Bases Using Surface Enhanced Raman Spectroscopy
Post-translational modifications of DNA- changes in the chemical structure of individual bases that occur without changes in the DNA sequence- are known to alter gene expression. They are believed to result in frequently deleterious phenotypic changes, such as cancer. Methylation of adenine, methyla...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3888867/ https://ncbi.nlm.nih.gov/pubmed/24427449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jz201423b |
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