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Detecting Chemically Modified DNA Bases Using Surface Enhanced Raman Spectroscopy
Post-translational modifications of DNA- changes in the chemical structure of individual bases that occur without changes in the DNA sequence- are known to alter gene expression. They are believed to result in frequently deleterious phenotypic changes, such as cancer. Methylation of adenine, methyla...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3888867/ https://ncbi.nlm.nih.gov/pubmed/24427449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jz201423b |
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