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Effect of rotation on the diffusion-controlled rate of ligand-protein association.

The rate of binding a fairly large ligand molecule to a protein is reduced below the usual diffusion-controlled rate by the requirement of a certain rotational orientation. A simple, approximate treatment of this effect is given for special cases of spherical and ellipsoidal ligands. As the center o...

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Bibliografiska uppgifter
Huvudupphovsman: Hill, T L
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1975
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC388844/
https://ncbi.nlm.nih.gov/pubmed/1061081
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