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Evaluating the potential of cubosomal nanoparticles for oral delivery of amphotericin B in treating fungal infection

The oral administration of amphotericin B (AmB) has a major drawback of poor bioavailability. The aim of this study was to investigate the potential of glyceryl monoolein (GMO) cubosomes as lipid nanocarriers to improve the oral efficacy of AmB. Antifungal efficacy was determined in vivo in rats aft...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yang, Zhiwen, Chen, Meiwan, Yang, Muhua, Chen, Jian, Fang, Weijun, Xu, Ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3888350/
https://ncbi.nlm.nih.gov/pubmed/24421641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S54967
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