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Run-In Phase III Trial Design With Pharmacodynamics Predictive Biomarkers
BACKGROUND: Developments in biotechnology have stimulated the use of predictive biomarkers to identify patients who are likely to benefit from a targeted therapy. Several randomized phase III designs have been introduced for development of a targeted therapy using a diagnostic test. Most such design...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3888165/ https://ncbi.nlm.nih.gov/pubmed/24096624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djt265 |
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