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Malate dehydrogenase 2 confers docetaxel resistance via regulations of JNK signaling and oxidative metabolism
BACKGROUND: Resistance to chemotherapy represents a significant obstacle in prostate cancer therapeutics. Novel mechanistic understandings in cancer cell chemotherapeutic sensitivity and resistance can optimize treatment and improve patient outcome. Molecular alterations in the metabolic pathways ar...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3888097/ https://ncbi.nlm.nih.gov/pubmed/23389923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.22650 |
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