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Cellular levels of feedback regulator of adenylate cyclase and the effect of epinephrine and insulin.

We have obtained direct evidence that shows the cellular formation and subsequent release of a potent inhibitor (feedback regulator) of adenylate cyclase [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1] by adipocytes, upon stimulation with epinephrine. The appearance of such a feedback regulator in...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Ho, R j, Russell, T R, Asakawa, T, Sutherland, E W
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1975
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388806/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/174073/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.72.12.4739
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