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Inhibition of Endoplasmic Reticulum Associated Degradation Reduces Endoplasmic Reticulum Stress and Alters Lysosomal Morphology and Distribution
Disturbances in proteostasis are observed in many neurodegenerative diseases. This leads to activation of protein quality control to restore proteostasis, with a key role for the removal of aberrant proteins by proteolysis. The unfolded protein response (UPR) is a protein quality control mechanism o...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Korea Society for Molecular and Cellular Biology
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3887885/ https://ncbi.nlm.nih.gov/pubmed/23515578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-013-2286-9 |
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