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Do Sirtuins Promote Mammalian Longevity?: A Critical Review on Its Relevance to the Longevity Effect Induced by Calorie Restriction

Sirtuins (SIRTs), a family of nicotinamide adenine dinucleotide (NAD)-dependent deacetylases, are emerging as key molecules that regulate aging and age-related diseases including cancers, metabolic disorders, and neurodegenerative diseases. Seven isoforms of SIRT (SIRT1–7) have been identified in ma...

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Bibliografiset tiedot
Päätekijät: Park, Seongjoon, Mori, Ryoichi, Shimokawa, Isao
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Korea Society for Molecular and Cellular Biology 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887872/
https://ncbi.nlm.nih.gov/pubmed/23661364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-013-0130-x
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