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Sub-Toxic Dose of Apigenin Sensitizes HepG2 Cells to TRAIL through ERK-Dependent Up-Regulation of TRAIL Receptor DR5

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is regarded as a promising candidate for anticancer therapy due to its selective toxicity to cancer cells. Nevertheless, because of TRAIL resistance in some cancer cells, combined treatment with sensitizing agents is required to enhance...

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Bibliographic Details
Main Authors: Kim, Eun Young, Yu, Ji Sun, Yang, Mihi, Kim, An Keun
Format: Artigo
Language:Inglês
Published: Korea Society for Molecular and Cellular Biology 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887848/
https://ncbi.nlm.nih.gov/pubmed/23224239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-013-2175-2
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