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The Transmembrane Adaptor Protein, Linker for Activation of T cells (LAT), Regulates RANKL-Induced Osteoclast Differentiation
RANKL induces the formation of osteoclasts, which are responsible for bone resorption. Herein we investigate the role of the transmembrane adaptor proteins in RANKL-induced osteoclastogenesis. LAT positively regulates osteoclast differentiation and is up-regulated by RANKL via c-Fos and NFATc1, wher...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Korea Society for Molecular and Cellular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3887798/ https://ncbi.nlm.nih.gov/pubmed/22382685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-012-0009-2 |
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