The Transmembrane Adaptor Protein, Linker for Activation of T cells (LAT), Regulates RANKL-Induced Osteoclast Differentiation

RANKL induces the formation of osteoclasts, which are responsible for bone resorption. Herein we investigate the role of the transmembrane adaptor proteins in RANKL-induced osteoclastogenesis. LAT positively regulates osteoclast differentiation and is up-regulated by RANKL via c-Fos and NFATc1, wher...

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Bibliografiska uppgifter
Huvudupphovsmän: Kim, Kabsun, Kim, Jung Ha, Moon, Jang Bae, Lee, Jongwon, Kwak, Han bok, Park, Yong-Wook, Kim, Nacksung
Materialtyp: Artigo
Språk:Inglês
Publicerad: Korea Society for Molecular and Cellular Biology 2012
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887798/
https://ncbi.nlm.nih.gov/pubmed/22382685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-012-0009-2
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