Extracellular HIV-1 Tat Induces Human Beta-Defensin-2 Production Via NF-kappaB/AP-1 Dependent Pathways in Human B Cells

Defensins, a family of antimicrobial peptides, are one of the first lines of host defense. Human beta-defensins (hBD) such as hBD-2 and -3 have anti-HIV activity. Previous studies have shown that HIV-1 virion can induce the expression of hBD, although the exact components of HIV-1 virion that are re...

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Bibliografiska uppgifter
Huvudupphovsmän: Ju, Sung Mi, Goh, Ah Ra, Kwon, Dong-Joo, Youn, Gi Soo, Kwon, Hyung-Joo, Bae, Yong Soo, Choi, Soo Young, Park, Jinseu
Materialtyp: Artigo
Språk:Inglês
Publicerad: Korea Society for Molecular and Cellular Biology 2012
Ämnen:
Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887796/
https://ncbi.nlm.nih.gov/pubmed/22450687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-012-2287-0
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