PI3-Kinase/p38 Kinase-Dependent E2F1 Activation Is Critical for Pin1 Induction in Tamoxifen-Resistant Breast Cancer Cells

Acquired resistance to tamoxifen (TAM) is a serious therapeutic problem in breast cancer patients. We have shown that Pin1, a peptidyl prolyl isomerase, is consistently overexpressed in TAM-resistant MCF-7 cells (TAMR-MCF-7 cells) and plays a key role in the enhanced angiogenic potential of TAMR-MCF...

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Bibliografiset tiedot
Päätekijät: Lee, Kwang Youl, Lee, Jeong Woon, Nam, Hyun Jeong, Shim, Jeong-Hyun, Song, Youngsup, Kang, Keon Wook
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Korean Society for Molecular and Cellular Biology 2011
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887657/
https://ncbi.nlm.nih.gov/pubmed/21573702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-011-0074-y
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