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Efficient Nazarov Cyclization/Wagner-Meerwein Rearrangement Terminated by a Cu(II)-Promoted Oxidation: Synthesis of 4-Alkylidene Cyclopentenones

The discovery and elucidation of a novel Nazarov cyclization/Wagner-Meerwein rearrangement/oxidation sequence is described, which constitutes an efficient strategy for the synthesis of 4-alkylidene cyclopentenones. DFT computations and EPR experiments were conducted to gain further mechanistic insig...

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Autors principals: Lebœuf, David, Theiste, Eric, Gandon, Vincent, Daifuku, Stephanie L., Neidig, Michael L., Frontier, Alison J.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887475/
https://ncbi.nlm.nih.gov/pubmed/23436470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201203396
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