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Transcription, Translation, and Function of Lubricin, a Boundary Lubricant, at the Ocular Surface

IMPORTANCE: Lubricin may be an important barrier to the development of corneal and conjunctival epitheliopathies that may occur in dry eye disease and contact lens wear. OBJECTIVE: To test the hypotheses that lubricin (ie, proteoglycan 4 [PRG4]), a boundary lubricant, is produced by ocular surface e...

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Bibliographic Details
Main Authors: Schmidt, Tannin A., Sullivan, David A., Knop, Erich, Richards, Stephen M., Knop, Nadja, Liu, Shaohui, Sahin, Afsun, Darabad, Raheleh Rahimi, Morrison, Sheila, Kam, Wendy R., Sullivan, Benjamin D.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887468/
https://ncbi.nlm.nih.gov/pubmed/23599181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaophthalmol.2013.2385
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