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Glutathione Peroxidase Mimic Ebselen Improves Glucose-Stimulated Insulin Secretion in Murine Islets

Aims: Glutathione peroxidase (GPX) mimic ebselen and superoxide dismutase (SOD) mimic copper diisopropylsalicylate (CuDIPs) were used to rescue impaired glucose-stimulated insulin secretion (GSIS) in islets of GPX1 and(or) SOD1-knockout mice. Results: Ebselen improved GSIS in islets of all four test...

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Bibliografiska uppgifter
Huvudupphovsmän: Wang, Xinhui, Yun, Jun-Won, Lei, Xin Gen
Materialtyp: Artigo
Språk:Inglês
Publicerad: Mary Ann Liebert, Inc. 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887434/
https://ncbi.nlm.nih.gov/pubmed/23795780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5361
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