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An anti-leishmanial thiadiazine agent induces multiple myeloma cell apoptosis by suppressing the nuclear factor kappaB signalling pathway
BACKGROUND: Nuclear factor κB (NFκB) has a critical role in the pathophysiology of multiple myeloma. Targeting NFκB is an important strategy for anti-myeloma drug discovery. METHODS: Luciferase assay was used to evaluate the effects of DETT on NFκB activity. Annexin V–PI double staining and immunobl...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3887303/ https://ncbi.nlm.nih.gov/pubmed/24231956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.711 |
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