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Gemcitabine enhances the efficacy of reovirus-based oncotherapy through anti-tumour immunological mechanisms
BACKGROUND: Reovirus preferentially infects and kills cancer cells and is currently undergoing clinical trials internationally. While oncolysis is the primary mode of tumour elimination, increasing evidence illustrates that reovirus additionally stimulates anti-tumour immunity with a capacity to tar...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3887295/ https://ncbi.nlm.nih.gov/pubmed/24281006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.695 |
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