MicroRNA-133a regulates the mRNAs of two invadopodia-related proteins, FSCN1 and MMP14, in esophageal cancer

BACKGROUND: FSCN1 and matrix metalloproteinase 14 (MMP14) are both invadopodia-related proteins. We herein elucidate the tumourigenicity of these proteins and identify novel therapeutic agents in esophageal squamous cell carcinoma (ESCC). METHODS: FSCN1 and MMP14 were evaluated by immunohistochemist...

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Hlavní autoři: Akanuma, N, Hoshino, I, Akutsu, Y, Murakami, K, Isozaki, Y, Maruyama, T, Yusup, G, Qin, W, Toyozumi, T, Takahashi, M, Suito, H, Hu, X, Sekino, N, Matsubara, H
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
Témata:
Molecular Diagnostics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887287/
https://ncbi.nlm.nih.gov/pubmed/24196787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.676
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