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Interleukin-4 Induces Up-regulation of Endothelial Cell Claudin-5 through Activation of FoxO1: ROLE IN PROTECTION FROM COMPLEMENT-MEDIATED INJURY
Injury to endothelial cells (ECs) often results in cell retraction and gap formation. When caused by antigen aggregation or complement, this injury can be prevented by pretreatment of the ECs with IL-4, suggesting that IL-4 modifies the intercellular junction. Therefore, we investigated the effects...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3887209/ https://ncbi.nlm.nih.gov/pubmed/24280217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.455766 |
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